Monday, January 23, 2012

Costa Concordia: As Hope Fades for More Survivors, Finger-Pointing Begins (Time.com)

As hope fades for the successful rescue of the 20 people still missing a week after the wreck of the Costa Concordia cruise ship, the focus of operations on the Italian island of Giglio is shifting towards the prevention of future catastrophe and the allocation of blame for that which has already occurred. With some 500,000 gallons of fuel oil still sloshing around in the hull of the ship, "We need to prevent an environmental disaster," says Franco Gabrielli, the head of Italy's civil protection agency, who is coordinating the emergency response. He added that while the agency wasn't giving up rescue attempts, the risk of rupture of the ship's fuel tanks was becoming an increasingly important worry.

Rescuers have been investigating whether the ship can be chained to the rocks on which it capsized last week, to halt its slow slippage towards deep waters, which would dramatically complicate further salvage efforts. The consequences of an oil spill would be disastrous. The mayor of Giglio has called the ship an "ecological time bomb." The potential for pollution puts at risk not only the area around the tiny Mediterranean island, but also the entirety of the nearby coast of Tuscany, one of the engines of Italian tourism. On Saturday, light oil was discovered floating near the Concordia, but rescue workers speculated it may have been diesel from rescue boats or lubricant from some of the on board machinery, not the heavy engine oil that could spell environmental devastation. (Photos: The Sinking of the Costa Concordia)

The plan is to extract the fuel oil and replace it with water, to avoid destabilizing the ship. Experts estimate that draining even those tanks closest to the outside of the hull could take as much as month -- providing storms don't cause delays -- and that the inner tanks could prove harder to reach. Still, "there is a very good chance that the fuel oil can be removed," says Paul Wright, associate director of the Marine Institute at Britain's Plymouth University. Contamination from the kitchen oils, chemicals, sewage, and personal belongings of the crew and passengers are likely to be contained using booms. What could prove more challenging is the salvage operation of the $450 million ship itself. "I would be very surprised if she is righted and floated off," says Wright. "The most likely solution is that she will be cut up and dismantled in position." It's an operation that could take months.

Meanwhile, the legal process is gearing up as Italian authorities work to establish the criminal liability for what some experts predict will produce the most expensive insurance claims in maritime history. As of Saturday, the death toll for the accident stands at 12 and is likely to rise; the Costa Concordia's captain, Francesco Schettino, is under house arrest and facing charges of manslaughter. At the heart of the investigation will be determining what happened in the 70 minutes between the moment the ship tore itself open on the rocks and Schettino's first formal call for help. In the interval, the coast guard was misinformed by a member of the Concordia's crew about the condition of ship, even as it was taking on water. And passengers were told by an apparently confused or oblivious crew that the problem had been resolved and that they should return to their rooms. (History's Greatest Cruise Ship Disasters)

Lawyers for civil plaintiffs will be eager to show that responsibility for the tragedy extends beyond the incompetence of the captain. "You have an incentive to find the deep pockets," says Luca Melchionna, a professor at St. John's University School of Law. Was the Costa Concordia's dangerous approach to the island part of a pattern that the cruise company had previously sanctioned or tolerated? To what extent did company policy contribute to the disarray in the early minutes when lives could have been saved? How well prepared were the crew for the event of an emergency?

For now, the cruise company has joined the criminal case against the captain as a civil party, formally putting itself among the injured and (not coincidentally) forestalling civil action in Italy while the criminal trial plays out, something that could take months of years. "It's a strategic legal move that protects them, at least for a while," says Melchionna. But such maneuvers won't protect the company in other jurisdictions. While lawyers for potential plaintiffs have complained that the waivers their clients were asked to sign have ruthlessly limited the cruise line's liability, at least two law firms have announced they plan to file a class action lawsuit in the U.S. next week. Meanwhile, several passengers have already sought representation with the British law firm Irwin Mitchell. "With thousands of passengers and crew on board this huge vessel, their safety should have been the first and only priority," Clive Garner, the head of the firm's international law team, said in a statement. "Tragically, it seems that this was not the case and passengers and their families have paid a very heavy price."

Transcript: 'Go On Board!' Coast Guard Tells Cruise Ship Captain

WATCH: Crew Tells Passengers, 'Return to Your Cabin'

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Source: http://us.rd.yahoo.com/dailynews/rss/science/*http%3A//news.yahoo.com/s/time/20120123/wl_time/08599210502900

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Fundamental malaria discovery: How parasites target proteins to surface of red blood cells

ScienceDaily (Jan. 20, 2012) ? A team of researchers led by Kasturi Haldar and Souvik Bhattacharjee of the University of Notre Dame's Center for Rare and Neglected Diseases has made a fundamental discovery in understanding how malaria parasites cause deadly disease.

The researchers show how parasites target proteins to the surface of the red blood cell that enables sticking to and blocking blood vessels. Strategies that prevent this host-targeting process will block disease.

The research findings appear in the Jan. 20 edition of the journal Cell. The study was supported by the National Institutes of Health.

Malaria is a blood disease that kills nearly 1 million people each year. It is caused by a parasite that infects red cells in the blood. Once inside the cell, the parasite exports proteins beyond its own plasma membrane border into the blood cell. These proteins function as adhesins that help the infected red blood cells stick to the walls of blood vessels in the brain and cause cerebral malaria, a deadly form of the disease that kills over half a million children each year.

In all cells, proteins are made in a specialized cell compartment called the endoplasmic reticulum (ER) from where they are delivered to other parts of the cell. Haldar and Bhattacharjee and collaborators Robert Stahelin at the Indiana University School of Medicine-South Bend (who also is an adjunct faculty member in Notre Dame's Department of Chemistry and Biochemistry), and David and Kaye Speicher at the University of Pennsylvania's Wistar Institute discovered that for host-targeted malaria proteins the very first step is binding to the lipid phosphatidylinositol 3-phosphate, PIP, in the ER.

This was surprising for two reasons. Previous studies suggested an enzyme called Plasmepsin V that released the proteins into the ER was also the export mechanism. However, Haldar, Bhattacharjee and colleagues discovered that binding to PIP lipid which occurs first is the gate keeper to control export and that export can occur without Plasmepsin V action. Further, in higher eukaryotic cells (such as in humans), the lipid PIP is not usually found within the ER membrane but rather is exposed to the cellular cytoplasm.

Haldar and Bhattacharjee are experts in malaria parasite biology and pathogenesis. Stahelin is an expert in PIP lipid biology, and David and Kaye Speicher are experts in proteomics and a method called mass spectrometry.

Their interdisciplinary collaboration reveals a fundamental, novel cellular function, whose disruption can provide new therapies that are urgently needed for malaria.

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The above story is reprinted from materials provided by University of Notre Dame. The original article was written by Pamela Tamez and William Gilroy.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Souvik Bhattacharjee, Robert?V. Stahelin, Kaye?D. Speicher, David?W. Speicher, Kasturi Haldar. Endoplasmic Reticulum PI(3)P Lipid Binding Targets Malaria Proteins to the Host Cell. Cell, 2012; 148 (1-2): 201 DOI: 10.1016/j.cell.2011.10.051

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/0ITSbQ2FgwQ/120120184532.htm

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Kodak bankruptcy dims once bright Hollywood star (Reuters)

LOS ANGELES (Reuters) ? Kodak's star may never shine again in Hollywood.

The bankruptcy of the American icon that invented the handheld camera is reverberating beyond Wall Street and around the world's entertainment capital. Insiders say Hollywood may be on the verge of scaling back a decades-old symbiotic relationship, and seeking business alternatives.

Kodak's star began to fade in the late 1990s as digital technology began chipping away at its century-long stronghold on film distribution. But the company still provides a significant amount of film to Hollywood and it remains a presence in the land of make-believe, where the Kodak Theater is home to the Oscars.

Sources say major studios - listed among Kodak's top unsecured creditors - fear they will not get repaid and have started to look elsewhere to buy film.

Major entertainment companies listed among Kodak's top 50 unsecured creditors include Sony, owed $16.7 million; Warner Brothers, due $14.2 million; NBC Universal, short $9.3 million; Paramount Studios, owed $6.8 million; and Walt Disney Studios, $4.2 million.

Two sources with knowledge of the contracts say most of these debts are related to film rebates owed to the studios who buy film from Kodak on a picture-by-picture basis. The price of film varies and often drops as a studio uses more, which is why they are often owed rebates.

None of the studios wished to comment.

HEDGING BETS

One source, who works for a company that buys film from Kodak, said studios have been stockpiling Kodak film in anticipation of a bankruptcy filing. Now, they are also talking with other film suppliers, like Fuji.

At its peak, Kodak probably generated about $500 million from film distribution for motion pictures annually, experts estimate.

In addition to setting the standard for 35mm film, Kodak also won numerous Oscars for technical achievement. Its founder, George Eastman, was named an honorary member of the Academy of Motion Picture Arts and Sciences.

Chris McGurk, CEO of Cinedigm and former COO of Metro-Goldwyn-Mayer Inc, said that in the late 1990s, studios, filmmakers and theater chains stepped up efforts to digitize movies, eventually rendering Kodak's staple 35 mm film a relic of the past.

"Kodak failed to recognize the game-changing impact the digital technology would have on the film-making business. Those who didn't see it have fallen by the wayside," McGurk said.

"It's easy to see how that could happen. Industry has been resistant to change and projection film on 35 mm had been happening for 75 years but the fact is that the world has changed and digital takes enormous costs out of the distribution system."

WIDENING RIPPLES

Beyond mere film supply, speculation persists that the Academy of Motion Picture Arts and Sciences, which hosts the Oscars, may exercise an option in its contract that allows it to find a new home for Hollywood's glitziest awards show.

About 10 years ago, Kodak agreed to pay $75 million to developers to see its name on the 3,400-plus-seat theater.

The Academy said it has not begun venue negotiations for the Oscar telecast beyond 2013. But many industry watchers feel the Oscars may want to disassociate itself from Kodak - or prepare for the company to become a punchline at the upcoming Academy Awards.

"I don't think it's good branding at all for the Oscars to be associated with a bankrupt company," branding expert Adam Hanft said.

The ripples of the bankruptcy extend even to the Magic Kingdom. In 2002, Kodak and Disney renewed a multiyear promotion accord first set in 1989, which marketing experts said could be valued at tens of millions of dollars.

Under the original deal, Kodak paid Disney for the rights to use Disney characters in promotions and advertisements worldwide, and to advertise its products on Disney's cable television channel and in Disney publications.

In 2002, the companies renewed their alliance and provided for sales and promotion at Disney properties of traditional film and one-time use cameras and other services.

Bankruptcy lawyer Edward Neiger said this deal could be revisited as well.

"One of the biggest assets that Kodak has going for it is its brand-name recognition and its goodwill. Very few companies have the name recognition that Kodak has. It's up there with Xerox and General Motors," he said.

"In its bankruptcy, Kodak will analyze whether they're getting the right bang for their buck with these arrangements, or whether the money could be better spent elsewhere, for example, on R&D."

(Reporting By Susan Zeidler; Editing by Gary Hill)

Source: http://us.rd.yahoo.com/dailynews/rss/movies/*http%3A//news.yahoo.com/s/nm/20120120/en_nm/us_kodak_hollywood

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Sunday, January 22, 2012

Abortion doctor facing murder charge free on bail

By The Associated Press and msnbc.com staff

Lawyers for a Utah abortion doctor charged with murder for the death of a fetus in Maryland asked a judge Friday to throw out the charges, arguing she is immune from prosecution and that the state is trying to infringe upon a woman's right to terminate a pregnancy.

Dr. Nicola Riley and her former colleague, Dr. Steven Brigham of New Jersey, were indicted last month under a law that allows murder charges to be brought in the death of a viable fetus. The 2005 law had only been used previously for cases in which defendants were accused of assaulting or killing pregnant women, and prosecutors have acknowledged they are in uncharted territory by using it to charge doctors who perform abortionds. Thirty-seven other states have similar statutes.

At Riley's bail review hearing Friday in Cecil County Circuit Court in Elkton, Md., attorney Stuart O. Simms argued that prosecutors were attempting to criminalize constitutionally protected medical treatment.

"Based on their interpretation of the statute, they are now threatening to charge any medical professional in Cecil County with a state crime," Simms told The Associated Press after the hearing.

Court: No forced abortion for Mass. woman

In Maryland, licensed physicians can perform abortions before the fetus is deemed capable of surviving outside the womb, and abortions of viable fetuses are permitted to protect the life or health of the mother or if the fetus has serious genetic abnormalities.

The state's fetal homicide law was approved in 2005 in the wake of the highly publicized slaying of Laci Peterson in Modesto, Calif. Peterson was seven months pregnant, and her husband, Scott Peterson, was convicted of killing both her and their unborn son.

The law specifically exempts licensed physicians performing abortions. Before the bill was passed, its sponsor, Delegate Charles Boutin, wrote in a letter to a committee chairman that it is "clearly and solely a victim's rights bill. It takes care of the 'Laci Peterson' issue in Maryland, while protecting a woman's right to choose."

Judge Keith Baynes set bail for Riley at $300,000, the amount requested by Deputy State's Attorney Kerwin Miller, who argued that the evidence against the 46-year-old Salt Lake City resident is strong and characterized her as a flight risk. She was arrested Dec. 28 on a fugitive warrant and was extradited to Maryland on Thursday.

She is charged with one count each of first- and second-degree murder stemming from an abortion in Elkton, Md., ?16 months ago involving a teenager who was 21 weeks pregnant, according to the Baltimore Sun.

"It gets no bigger than this," Miller said in reference to Riley's first-degree murder charge, the Cecil Whig of Elkton reported.

Miller also told the Cecil Whig that?the "evidence is overwhelming" in the case, because Riley admitted to performing the procedure to Union Hospital officials, according to a Maryland Board of Physicians report.

Riley posted bail shortly after the hearing and was released from custody. As a condition of her release, she was ordered not to perform abortions.

The charges against Riley stem from a botched abortion in August 2010 at Brigham's Elkton clinic. The 18-year-old patient suffered serious injuries, and Riley drove her to a nearby hospital rather than call 911, according to medical regulators. The fetus was 21 weeks old. Doctors generally consider fetuses to be viable outside the womb starting around 23 weeks.

Brigham, of Voorhees, N.J., has been charged with murder in the death of that fetus and four others. He was released from custody Jan. 6 after posting a $500,000 bond. His attorney has also argued that Brigham has not violated the fetal homicide law.

Anti-abortion activists have hailed the arrests of Brigham and Riley, saying the charges shed light on the troubling practices of certain abortion doctors. A search of Brigham's Elkton clinic revealed a freezer containing 35 late-term fetuses, including one believed to have been aborted at 36 weeks, according to documents released by medical regulators.

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Source: http://usnews.msnbc.msn.com/_news/2012/01/20/10200832-abortion-doctor-free-on-bail-after-being-charged-with-murder

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Iraq risks slipping into authoritarianism: rights group (Reuters)

BAGHDAD (Reuters) ? Iraq risks sliding back towards authoritarian rule with Shi'ite Prime Minister Nuri al-Maliki's security forces cracking down on protests, harassing opponents and torturing detainees, a U.S.-based human rights monitor said on Sunday.

In its annual world report, New York-based Human Rights Watch said Iraqi authorities had suppressed freedom of expression and assembly, beaten and detained anti-government protesters and run a secret prison where suspects are tortured.

The report was issued a month after the last U.S. troops left Iraq nearly nine years after the invasion that ousted Sunni dictator Saddam Hussein and allowed the country's Shi'ite majority to rise to power in an elected government.

"Iraq is quickly slipping back into authoritarianism as its security forces abuse protesters, harass journalists, and torture detainees," Sarah Leah Whitson from Human Rights Watch said in a statement released with the annual report.

"Despite U.S. government assurances that it helped create a stable democracy, the reality is that it left behind a budding police state."

A government spokesman did not have any immediate comment on the report.

Early last year, thousands protested across Iraq about a lack of basic services in demonstrations prompted in part by the Arab Spring against authoritarian rulers in the region.

At least 10 people were killed in one day of protests after security forces clamped down on protesters trying to storm government buildings. The most violent clashes were in the northern city of Mosul and Basra in the south.

The report also said journalists were often harassed.

It said authorities had raided a press freedom organization and journalists reporting on the protests had been arrested and beaten. In semi-autonomous Iraqi Kurdistan, the regional government had suppressed local journalists by using death threats and beatings, it said.

In February, Human Rights Watch said it had uncovered a secret detention facility controlled by Iraqi security forces, where detainees said they had been tortured, the report said. No officials were prosecuted for the abuses, it added.

Maliki, whose Shi'ite coalition dominates parliament, triggered a political crisis in December when his government ordered the arrest of a Sunni vice president and sought to oust one of his Sunni deputies.

The Shi'ite leader says the moves were not politically motivated. But some minority Sunnis fear they are increasingly sidelined from political power-sharing and that Maliki is trying to consolidate his own authority.

(Reporting by Patrick Markey)

Source: http://us.rd.yahoo.com/dailynews/rss/iraq/*http%3A//news.yahoo.com/s/nm/20120122/wl_nm/us_iraq_rights

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Gaming Everything ? Blog Archive ? Rumor: Ubisoft moved I Am ...

January 20th, 2012 Posted in 360, PS3, Rumors Posted By: Valay

I Am Alive has changed radically since it began development in 2008. Darkworks originally worked on the project before it was transferred to Ubisoft Shanghai, and the gameplay has undergone a massive overhaul.

I Am Alive was also planned as a retail title. When the title reemerged, however, Ubisoft announced that it would be released through the PlayStation Network and Xbox Live Arcade.

A Ubisoft insider speaking with PSM3 hinted that the move was made out of fear that the company would be competing with Sony?s The Last of Us.

The magazine wrote in its February issue:

?A Ubisoft insider suggests upcoming survive-?em-up I Am Alive was driven to PSN by fear of competing with PlayStation 3 survival adventure The Last of Us. Few can touch Naughty Dog?s production values and competing with them on shelves would be a bad move.?

The Last of Us was pretty much under wraps until it made its debut at the Spike VGAs late last year. If this rumor is true, it would be interesting to learn how Ubisoft heard about the title well before it was revealed.

Source: http://gamingeverything.com/14185/rumor-ubisoft-moved-i-am-alive-to-psnxbla-due-to-fear-of-competing-with-the-last-of-us/

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Saturday, January 21, 2012

FCC Fridays: January 20, 2012

We here at Engadget tend to spend a lot of way too much time poring over the latest FCC filings, be it on the net or directly on the ol' Federal Communications Commission's site. Since we couldn't possibly (want to) cover all the stuff that goes down there, we've gathered up an exhaustive listing of every phone and / or tablet getting the stamp of approval over the last week. Enjoy!

Continue reading FCC Fridays: January 20, 2012

FCC Fridays: January 20, 2012 originally appeared on Engadget on Fri, 20 Jan 2012 23:24:00 EDT. Please see our terms for use of feeds.

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